Inhibition of Slug effectively targets leukemia stem cells via the Slc13a3/ROS signaling pathway

Leukemia stem cells (LSCs) are rare populations of acute myeloid leukemia (AML) cells that are able to initiate, maintain and propagate AML. Targeting LSCs is a promising approach for preventing AML relapse and improving long-term outcomes. While Slug, a zinc-finger transcription repressor, negative...

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Publicado en:Leukemia
Main Authors: Zhang, Zhonghui, Li, Lei, Wu, Chen, Yin, Guoshu, Zhu, Pei, Zhou, Yalu, Hong, Yuanfan, Ni, Hongyu, Qian, Zhijian, Wu, Wen-Shu
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995768/
https://ncbi.nlm.nih.gov/pubmed/31492896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41375-019-0566-x
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