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A Novel Slug-containing Negative Feedback Loop regulates SCF/c-Kit-Mediated Hematopoietic Stem Cell Self-renewal
The SCF/c-Kit pathway has crucial roles in controlling hematopoietic stem cell (HSC) renewal. However, little is known about the intracellular regulation of the SCF/c-Kit pathway in HSCs. We report here that Slug, a zinc-finger transcription repressor, functions as a direct transcriptional repressor...
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Publicado no: | Leukemia |
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Main Authors: | , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5288275/ https://ncbi.nlm.nih.gov/pubmed/27451973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2016.201 |
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