MicroRNA-302/367 Cluster Governs hESC Self-Renewal by Dually Regulating Cell Cycle and Apoptosis Pathways

miR-302/367 is the most abundant miRNA cluster in human embryonic stem cells (hESCs) and can promote somatic cell reprogramming. However, its role in hESCs remains poorly understood. Here, we studied functional roles of the endogenous miR-302/367 cluster in hESCs by employing specific TALE-based tra...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Zhang, Zhonghui, Hong, Yuanfan, Xiang, Di, Zhu, Pei, Wu, Elise, Li, Wen, Mosenson, Jeffrey, Wu, Wen-Shu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400607/
https://ncbi.nlm.nih.gov/pubmed/25801506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.02.009
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