Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice

PURPOSE: The purpose of this study is to determine the effect of Cytoglobin (Cygb) deficiency on Crb1-related retinopathy. The Crb1 cell polarity complex is required for photoreceptor function and survival. Crb1-related retinopathies encompass a broad range of phenotypes which are not completely exp...

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Pubblicato in:Dev Biol
Autori principali: Kwon, Young Sam, Tham, Addy, Lopez, Antonio Jacobo, Edwards, Sydney, Woods, Sean, Chen, Jiajia, Fortunato, Jenna, Quiroz, Alejandra, Javier, Seanne, Au, Ingrid, Clarke, Maria, Humpal, Devin, Lloyd, K. C. Kent, Thomasy, Sara, Murphy, Christopher, Glaser, Thomas M., Moshiri, Ala
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995765/
https://ncbi.nlm.nih.gov/pubmed/31634437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.10.013
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