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Cytoglobin deficiency potentiates Crb1-mediated retinal degeneration in rd8 mice

PURPOSE: The purpose of this study is to determine the effect of Cytoglobin (Cygb) deficiency on Crb1-related retinopathy. The Crb1 cell polarity complex is required for photoreceptor function and survival. Crb1-related retinopathies encompass a broad range of phenotypes which are not completely exp...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Kwon, Young Sam, Tham, Addy, Lopez, Antonio Jacobo, Edwards, Sydney, Woods, Sean, Chen, Jiajia, Fortunato, Jenna, Quiroz, Alejandra, Javier, Seanne, Au, Ingrid, Clarke, Maria, Humpal, Devin, Lloyd, K. C. Kent, Thomasy, Sara, Murphy, Christopher, Glaser, Thomas M., Moshiri, Ala
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995765/
https://ncbi.nlm.nih.gov/pubmed/31634437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.10.013
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