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Intraoperative methadone in same-day ambulatory surgery: A randomized, double-blinded, dose-finding pilot study

BACKGROUND: Approximately 50 million US patients undergo ambulatory surgery annually. Postoperative opioid overprescribing is problematic, yet many patients report inadequate pain relief. In major inpatient surgery, intraoperative single-dose methadone produces better analgesia and reduces opioid us...

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Detalhes bibliográficos
Publicado no:Anesth Analg
Main Authors: Komen, Helga, Brunt, L. Michael, Deych, Elena, Blood, Jane, Kharasch, Evan D
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995343/
https://ncbi.nlm.nih.gov/pubmed/29847382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000003464
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