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Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease

One of the primary genetic risk factors for Alzheimer’s disease (AD) is the presence of the Ɛ4 allele of apolipoprotein E (APOE). APOE is a polymorphic lipoprotein that is a major cholesterol carrier in the brain. It is also involved in various cellular functions such as neuronal signaling, neuroinf...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Williams, Tosha, Borchelt, David R., Chakrabarty, Paramita
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995170/
https://ncbi.nlm.nih.gov/pubmed/32005122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-020-0358-9
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