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Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations

BACKGROUND: Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar molecular subtypes, we developed and validated a simple, mutually exclusive cla...

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Pubblicato in:BMC Cancer
Autori principali: Ruiz-Cordero, Roberto, Ma, Junsheng, Khanna, Abha, Lyons, Genevieve, Rinsurongkawong, Waree, Bassett, Roland, Guo, Ming, Routbort, Mark J., Zhang, Jianjun, Skoulidis, Ferdinandos, Heymach, John, Roarty, Emily B., Tang, Zhenya, Medeiros, L. Jeffrey, Patel, Keyur P., Luthra, Rajyalakshmi, Roy-Chowdhuri, Sinchita
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995064/
https://ncbi.nlm.nih.gov/pubmed/32005111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6579-z
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