Simplified molecular classification of lung adenocarcinomas based on EGFR, KRAS, and TP53 mutations

BACKGROUND: Gene expression profiling has consistently identified three molecular subtypes of lung adenocarcinoma that have prognostic implications. To facilitate stratification of patients with this disease into similar molecular subtypes, we developed and validated a simple, mutually exclusive cla...

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Udgivet i:BMC Cancer
Main Authors: Ruiz-Cordero, Roberto, Ma, Junsheng, Khanna, Abha, Lyons, Genevieve, Rinsurongkawong, Waree, Bassett, Roland, Guo, Ming, Routbort, Mark J., Zhang, Jianjun, Skoulidis, Ferdinandos, Heymach, John, Roarty, Emily B., Tang, Zhenya, Medeiros, L. Jeffrey, Patel, Keyur P., Luthra, Rajyalakshmi, Roy-Chowdhuri, Sinchita
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
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Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995064/
https://ncbi.nlm.nih.gov/pubmed/32005111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-6579-z
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