Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis

In multiple sclerosis plaques, oligodendroglial connexin (Cx) 47 constituting main gap junction channels with astroglial Cx43 is persistently lost. As mice with Cx47 single knockout exhibit no demyelination, the roles of Cx47 remain undefined. We aimed to clarify the effects of oligodendroglia-speci...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Zhao, Yinan, Yamasaki, Ryo, Yamaguchi, Hiroo, Nagata, Satoshi, Une, Hayato, Cui, Yiwen, Masaki, Katsuhisa, Nakamuta, Yuko, Iinuma, Kyoko, Watanabe, Mitsuru, Matsushita, Takuya, Isobe, Noriko, Kira, Jun-ichi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2020
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995029/
https://ncbi.nlm.nih.gov/pubmed/31932428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901294117
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