Oligodendroglial connexin 47 regulates neuroinflammation upon autoimmune demyelination in a novel mouse model of multiple sclerosis

In multiple sclerosis plaques, oligodendroglial connexin (Cx) 47 constituting main gap junction channels with astroglial Cx43 is persistently lost. As mice with Cx47 single knockout exhibit no demyelination, the roles of Cx47 remain undefined. We aimed to clarify the effects of oligodendroglia-speci...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zhao, Yinan, Yamasaki, Ryo, Yamaguchi, Hiroo, Nagata, Satoshi, Une, Hayato, Cui, Yiwen, Masaki, Katsuhisa, Nakamuta, Yuko, Iinuma, Kyoko, Watanabe, Mitsuru, Matsushita, Takuya, Isobe, Noriko, Kira, Jun-ichi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995029/
https://ncbi.nlm.nih.gov/pubmed/31932428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901294117
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