Imaging breast cancer using hyperpolarized carbon-13 MRI

Our purpose is to investigate the feasibility of imaging tumor metabolism in breast cancer patients using (13)C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized (13)C label exchange between injected [1-(13)C]pyruvate and the endogenous tumor lactate pool. Treatment-naïve breast canc...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Gallagher, Ferdia A., Woitek, Ramona, McLean, Mary A., Gill, Andrew B., Manzano Garcia, Raquel, Provenzano, Elena, Riemer, Frank, Kaggie, Joshua, Chhabra, Anita, Ursprung, Stephan, Grist, James T., Daniels, Charlie J., Zaccagna, Fulvio, Laurent, Marie-Christine, Locke, Matthew, Hilborne, Sarah, Frary, Amy, Torheim, Turid, Boursnell, Chris, Schiller, Amy, Patterson, Ilse, Slough, Rhys, Carmo, Bruno, Kane, Justine, Biggs, Heather, Harrison, Emma, Deen, Surrin S., Patterson, Andrew, Lanz, Titus, Kingsbury, Zoya, Ross, Mark, Basu, Bristi, Baird, Richard, Lomas, David J., Sala, Evis, Wason, James, Rueda, Oscar M., Chin, Suet-Feung, Wilkinson, Ian B., Graves, Martin J., Abraham, Jean E., Gilbert, Fiona J., Caldas, Carlos, Brindle, Kevin M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995024/
https://ncbi.nlm.nih.gov/pubmed/31964840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913841117
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