Imaging breast cancer using hyperpolarized carbon-13 MRI

Our purpose is to investigate the feasibility of imaging tumor metabolism in breast cancer patients using (13)C magnetic resonance spectroscopic imaging (MRSI) of hyperpolarized (13)C label exchange between injected [1-(13)C]pyruvate and the endogenous tumor lactate pool. Treatment-naïve breast canc...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gallagher, Ferdia A., Woitek, Ramona, McLean, Mary A., Gill, Andrew B., Manzano Garcia, Raquel, Provenzano, Elena, Riemer, Frank, Kaggie, Joshua, Chhabra, Anita, Ursprung, Stephan, Grist, James T., Daniels, Charlie J., Zaccagna, Fulvio, Laurent, Marie-Christine, Locke, Matthew, Hilborne, Sarah, Frary, Amy, Torheim, Turid, Boursnell, Chris, Schiller, Amy, Patterson, Ilse, Slough, Rhys, Carmo, Bruno, Kane, Justine, Biggs, Heather, Harrison, Emma, Deen, Surrin S., Patterson, Andrew, Lanz, Titus, Kingsbury, Zoya, Ross, Mark, Basu, Bristi, Baird, Richard, Lomas, David J., Sala, Evis, Wason, James, Rueda, Oscar M., Chin, Suet-Feung, Wilkinson, Ian B., Graves, Martin J., Abraham, Jean E., Gilbert, Fiona J., Caldas, Carlos, Brindle, Kevin M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995024/
https://ncbi.nlm.nih.gov/pubmed/31964840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913841117
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