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Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells
The misfolding and aggregation of the largely disordered protein, α-synuclein, is a central pathogenic event that occurs in the synucleinopathies, a group of neurodegenerative disorders that includes Parkinson's disease. While there is a clear link between protein misfolding and neuronal vulner...
Gardado en:
| Publicado en: | Dis Model Mech |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6994945/ https://ncbi.nlm.nih.gov/pubmed/31848207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.040899 |
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