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HCT116 colorectal liver metastases exacerbate muscle wasting in a mouse model for the study of colorectal cancer cachexia

Colorectal cancer (CRC) is often accompanied by formation of liver metastases (LM) and skeletal muscle wasting, i.e. cachexia. Despite affecting the majority of CRC patients, cachexia remains underserved, understudied and uncured. Animal models for the study of CRC-induced cachexia, in particular mo...

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Dettagli Bibliografici
Pubblicato in:Dis Model Mech
Autori principali: Huot, Joshua R., Novinger, Leah J., Pin, Fabrizio, Bonetto, Andrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994937/
https://ncbi.nlm.nih.gov/pubmed/31915140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.043166
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