Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity

Fibroblast growth factor (FGF)13, a nonsecreted, X-linked, FGF homologous factor, is differentially expressed in adipocytes in response to diet, yet Fgf13’s role in metabolism has not been explored. Heterozygous Fgf13 knockouts fed normal chow and housed at 22°C showed hyperactivity accompanying red...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Sinden, Daniel S., Holman, Corey D., Bare, Curtis J., Sun, Xiaolu, Gade, Aravind R., Cohen, David E., Pitt, Geoffrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994920/
https://ncbi.nlm.nih.gov/pubmed/31339804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901178R
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