Knockout of the X-linked Fgf13 in the hypothalamic paraventricular nucleus impairs sympathetic output to brown fat and causes obesity

Fibroblast growth factor (FGF)13, a nonsecreted, X-linked, FGF homologous factor, is differentially expressed in adipocytes in response to diet, yet Fgf13’s role in metabolism has not been explored. Heterozygous Fgf13 knockouts fed normal chow and housed at 22°C showed hyperactivity accompanying red...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Sinden, Daniel S., Holman, Corey D., Bare, Curtis J., Sun, Xiaolu, Gade, Aravind R., Cohen, David E., Pitt, Geoffrey S.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994920/
https://ncbi.nlm.nih.gov/pubmed/31339804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901178R
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