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A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily

By recognizing members in the tumor necrosis factor (TNF) receptor superfamily, TNF ligand proteins function as extracellular cytokines to activate various signaling pathways involved in inflammation, proliferation, and apoptosis. Most ligands in TNF superfamily are trimeric and can simultaneously b...

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Vydáno v:Comput Struct Biotechnol J
Hlavní autoři: Su, Zhaoqian, Wu, Yinghao
Médium: Artigo
Jazyk:Inglês
Vydáno: Research Network of Computational and Structural Biotechnology 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994755/
https://ncbi.nlm.nih.gov/pubmed/32021664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.12.016
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