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A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily

By recognizing members in the tumor necrosis factor (TNF) receptor superfamily, TNF ligand proteins function as extracellular cytokines to activate various signaling pathways involved in inflammation, proliferation, and apoptosis. Most ligands in TNF superfamily are trimeric and can simultaneously b...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Su, Zhaoqian, Wu, Yinghao
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994755/
https://ncbi.nlm.nih.gov/pubmed/32021664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2019.12.016
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