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Repeated intramuscular transplantations of hUCB-MSCs improves motor function and survival in the SOD1 G(93)A mice through activation of AMPK

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is characterized by loss of motor neurons and degeneration of neuromuscular junctions. To improve disease progression, previous studies have suggested many options that have shown beneficial effects in diseases, especially...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kook, Myung Geun, Lee, SeungEun, Shin, Nari, Kong, Dasom, Kim, Da-Hyun, Kim, Min-Soo, Kang, Hyun Kyoung, Choi, Soon Won, Kang, Kyung-Sun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994691/
https://ncbi.nlm.nih.gov/pubmed/32005848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58221-1
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