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Synergistic effects of repair, resilience and retention of damage determine the conditions for replicative ageing

Accumulation of damaged proteins is a hallmark of ageing, occurring in organisms ranging from bacteria and yeast to mammalian cells. During cell division in Saccharomyces cerevisiae, damaged proteins are retained within the mother cell, resulting in an ageing mother while a new daughter cell exhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Borgqvist, Johannes, Welkenhuysen, Niek, Cvijovic, Marija
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994596/
https://ncbi.nlm.nih.gov/pubmed/32005954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58444-2
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