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The synergy of damage repair and retention promotes rejuvenation and prolongs healthy lifespans in cell lineages
Damaged proteins are inherited asymmetrically during cell division in the yeast Saccharomyces cerevisiae, such that most damage is retained within the mother cell. The consequence is an ageing mother and a rejuvenated daughter cell with full replicative potential. Daughters of old and damaged mother...
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| Publicado no: | PLoS Comput Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7598927/ https://ncbi.nlm.nih.gov/pubmed/33044956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008314 |
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