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A bispecific IgG format containing four independent antigen binding sites

Bispecific antibodies come in many different formats, including the particularly interesting two-in-one antibodies, where one conventional IgG binds two different antigens. The IgG format allows these antibodies to mediate Fc-related functionality, and their wild-type structure ensures low immunogen...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ljungars, Anne, Schiött, Torbjörn, Mattson, Ulrika, Steppa, Jessica, Hambe, Björn, Semmrich, Monika, Ohlin, Mats, Tornberg, Ulla-Carin, Mattsson, Mikael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994471/
https://ncbi.nlm.nih.gov/pubmed/32005942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58150-z
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