Off-the-shelf EBV-specific T cell immunotherapy for rituximab-refractory EBV-associated lymphoma following transplantation

BACKGROUND: Adoptive transfer of donor-derived EBV-specific cytotoxic T-lymphocytes (EBV-CTLs) can eradicate EBV-associated lymphomas (EBV-PTLD) after transplantation of hematopoietic cell (HCT) or solid organ (SOT) but is unavailable for most patients. METHODS: We developed a third-party, allogenei...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Prockop, Susan, Doubrovina, Ekaterina, Suser, Stephanie, Heller, Glenn, Barker, Juliet, Dahi, Parastoo, Perales, Miguel A., Papadopoulos, Esperanza, Sauter, Craig, Castro-Malaspina, Hugo, Boulad, Farid, Curran, Kevin J., Giralt, Sergio, Gyurkocza, Boglarka, Hsu, Katharine C., Jakubowski, Ann, Hanash, Alan M., Kernan, Nancy A., Kobos, Rachel, Koehne, Guenther, Landau, Heather, Ponce, Doris, Spitzer, Barbara, Young, James W., Behr, Gerald, Dunphy, Mark, Haque, Sofia, Teruya-Feldstein, Julie, Arcila, Maria, Moung, Christine, Hsu, Susan, Hasan, Aisha, O’Reilly, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Clinical Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994129/
https://ncbi.nlm.nih.gov/pubmed/31689242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121127
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