Follicular T helper cells shape the HCV-specific CD4(+) T cell repertoire after virus elimination

BACKGROUND: Chronic hepatitis C virus (HCV) infection is characterized by a severe impairment of HCV-specific CD4(+) T cell help that is driven by chronic antigen stimulation. We aimed to study the fate of HCV-specific CD4(+) T cells after virus elimination. METHODS: HCV-specific CD4(+) T cell respo...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Smits, Maike, Zoldan, Katharina, Ishaque, Naveed, Gu, Zuguang, Jechow, Katharina, Wieland, Dominik, Conrad, Christian, Eils, Roland, Fauvelle, Catherine, Baumert, Thomas F., Emmerich, Florian, Bengsch, Bertram, Neumann-Haefelin, Christoph, Hofmann, Maike, Thimme, Robert, Boettler, Tobias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2020
Onderwerpen:
Clinical Medicine
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994124/
https://ncbi.nlm.nih.gov/pubmed/31697649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129642
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