Hepatitis C virus–specific CD4(+) T cell phenotype and function in different infection outcomes

CD4(+) T cell failure is a hallmark of chronic hepatitis C virus (HCV) infection. However, the mechanisms underlying the impairment and loss of virus-specific CD4(+) T cells in persisting HCV infection remain unclear. Here we examined HCV-specific CD4(+) T cells longitudinally during acute infection...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Chen, Diana Y., Wolski, David, Aneja, Jasneet, Matsubara, Lyndon, Robilotti, Brandon, Hauck, Garrett, de Sousa, Paulo Sergio Fonseca, Subudhi, Sonu, Fernandes, Carlos Augusto, Hoogeveen, Ruben C., Kim, Arthur Y., Lewis-Ximenez, Lia, Lauer, Georg M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Concise Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994113/
https://ncbi.nlm.nih.gov/pubmed/31904582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI126277
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