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An improved method for detecting telomere size differences in T-lymphocyte interphases from older people with Down syndrome with and without mild cognitive impairment

Telomere size (quantified by fluorescence intensity and physical lengths) in short-term T-lymphocyte cultures from adults with Down syndrome (DS) with and without mild cognitive impairment (MCI-DS) or dementia was compared. For these studies, dementia status was determined based on longitudinal asse...

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Detalhes bibliográficos
Publicado no:Biol Methods Protoc
Main Authors: Jenkins, E. C., Ye, L., Marchi, E., Krinsky-McHale, S. J., Zigman, W. B., Schupf, N., Silverman, W. P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6994080/
https://ncbi.nlm.nih.gov/pubmed/32161788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomethods/bpx005
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