Increased “Absence” of Telomeres may Indicate Alzheimer’s Disease/Dementia Status in Older Individuals with Down syndrome

We have reported previously that telomeres (ends of chromosomes consisting of highly conserved TTAGGG repeats) were shorter in metaphase and interphase preparations in T lymphocytes from short-term whole blood cultures of women with Down syndrome (DS) and dementia compared to age-matched women with...

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Hauptverfasser: Jenkins, Edmund C., Ye, Lingling, Gu, Hong, Ni, Samantha A., Duncan, Charlotte J., Velinov, Milen, Pang, Deborah, Krinsky-McHale, Sharon J., Zigman, Warren B., Schupf, Nicole, Silverman, Wayne P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614684/
https://ncbi.nlm.nih.gov/pubmed/18571319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.05.098
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