Increased “Absence” of Telomeres may Indicate Alzheimer’s Disease/Dementia Status in Older Individuals with Down syndrome

We have reported previously that telomeres (ends of chromosomes consisting of highly conserved TTAGGG repeats) were shorter in metaphase and interphase preparations in T lymphocytes from short-term whole blood cultures of women with Down syndrome (DS) and dementia compared to age-matched women with...

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Autori principali: Jenkins, Edmund C., Ye, Lingling, Gu, Hong, Ni, Samantha A., Duncan, Charlotte J., Velinov, Milen, Pang, Deborah, Krinsky-McHale, Sharon J., Zigman, Warren B., Schupf, Nicole, Silverman, Wayne P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614684/
https://ncbi.nlm.nih.gov/pubmed/18571319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2008.05.098
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