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Pathogenesis of paclitaxel-induced peripheral neuropathy: A current review of in vitro and in vivo findings using rodent and human model systems

Paclitaxel (Brand name Taxol) is widely used in the treatment of common cancers like breast, ovarian and lung cancer. Although highly effective in blocking tumor progression, paclitaxel also causes peripheral neuropathy as a side effect in 60–70% of chemotherapy patients. Recent efforts by numerous...

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Publicat a:Exp Neurol
Autors principals: Staff, Nathan P., Fehrenbacher, Jill C., Caillaud, Martial, Damaj, M. Imad, Segal, Rosalind A., Rieger, Sandra
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993945/
https://ncbi.nlm.nih.gov/pubmed/31758983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113121
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