Knockdown of formin mDia2 alters lamin B1 levels and increases osteogenesis in stem cells

Nuclear actin plays a critical role in mediating mesenchymal stem cell (MSC) fate commitment. In marrow-derived MSCs, the principal diaphanous-related formin Diaph3 (mDia2) is present in the nucleus and regulates intranuclear actin polymerization, whereas Diaph1 (mDia1) is localized to the cytoplasm...

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Bibliografske podrobnosti
izdano v:Stem Cells
Main Authors: Sankaran, Jeyantt S., Sen, Buer, Dudakovic, Amel, Paradise, Christopher R., Perdue, Tony, Xie, Zhihui, McGrath, Cody, Styner, Maya, Newberg, Joshua, Uzer, Gunes, van Wijnen, Andre J., Rubin, Janet
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993926/
https://ncbi.nlm.nih.gov/pubmed/31648392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3098
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