Intranuclear Actin Regulates Osteogenesis

Depolymerization of the actin cytoskeleton induces nuclear trafficking of regulatory proteins and global effects on gene transcription. We here show that in mesenchymal stem cells (MSCs), cytochalasin D treatment causes rapid cofilin-/importin-9-dependent transfer of G-actin into the nucleus. The co...

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Bibliografiske detaljer
Udgivet i:Stem Cells
Main Authors: Sen, Buer, Xie, Zhihui, Uzer, Gunes, Thompson, William R., Styner, Maya, Wu, Xin, Rubin, Janet
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788101/
https://ncbi.nlm.nih.gov/pubmed/26140478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2090
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