HUMBLE BEGINNINGS WITH BIG GOALS: SMALL MOLECULE SOLUBLE EPOXIDE HYDROLASE INHIBITORS FOR TREATING CNS DISORDERS

Soluble epoxide hydrolase (sEH) degrades epoxides of fatty acids including epoxyeicosatrienoic acid isomers (EETs), which are produced as metabolites of the cytochrome P450 branch of the arachidonic acid pathway. EETs exert a variety of largely beneficial effects in the context of inflammation and v...

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Detalhes bibliográficos
Publicado no:Prog Neurobiol
Main Authors: Zarriello, Sydney, Tuazon, Julian, Corey, Sydney, Schimmel, Samantha, Rajani, Mira, Gorsky, Anna, Incontri, Diego, Hammock, Bruce D., Borlongan, Cesar V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993804/
https://ncbi.nlm.nih.gov/pubmed/30447256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pneurobio.2018.11.001
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