Detection of EXP1-Specific CD4+ T Cell Responses Directed Against a Broad Range of Epitopes Including Two Promiscuous MHC Class II Binders During Acute Plasmodium falciparum Malaria

Background: T cells are thought to play a major role in conferring immunity against malaria. This study aimed to comprehensively define the breadth and specificity of the Plasmodium falciparum (P. falciparum)-specific CD4+ T cell response directed against the exported protein 1 (EXP1) in a cohort of...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Heide, Janna, Wildner, Nils H., Ackermann, Christin, Wittner, Melanie, Marget, Matthias, Sette, Alessandro, Sidney, John, Jacobs, Thomas, Schulze zur Wiesch, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993587/
https://ncbi.nlm.nih.gov/pubmed/32038611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03037
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