Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair long-distance sciatic nerve defects in rats

Autologous nerve transplantation, which is the gold standard for clinical treatment of peripheral nerve injury, still has many limitations. In this study, aligned chitosan fiber hydrogel (ACG) grafted with a bioactive peptide mixture consisting of RGI (Ac-RGIDKRHWNSQGG) and KLT (Ac-KLTWQELYQLKYKGIGG...

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Bibliographische Detailangaben
Veröffentlicht in:Theranostics
Hauptverfasser: Rao, Feng, Wang, Yanhua, Zhang, Dianying, Lu, Changfeng, Cao, Zheng, Sui, Jiajie, Wu, Mengjiao, Zhang, Yawen, Pi, Wei, Wang, Bo, Kou, Yuhui, Wang, Xiumei, Zhang, Peixun, Jiang, Baoguo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2020
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993237/
https://ncbi.nlm.nih.gov/pubmed/32042324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36272
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