Aligned chitosan nanofiber hydrogel grafted with peptides mimicking bioactive brain-derived neurotrophic factor and vascular endothelial growth factor repair long-distance sciatic nerve defects in rats

Autologous nerve transplantation, which is the gold standard for clinical treatment of peripheral nerve injury, still has many limitations. In this study, aligned chitosan fiber hydrogel (ACG) grafted with a bioactive peptide mixture consisting of RGI (Ac-RGIDKRHWNSQGG) and KLT (Ac-KLTWQELYQLKYKGIGG...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Rao, Feng, Wang, Yanhua, Zhang, Dianying, Lu, Changfeng, Cao, Zheng, Sui, Jiajie, Wu, Mengjiao, Zhang, Yawen, Pi, Wei, Wang, Bo, Kou, Yuhui, Wang, Xiumei, Zhang, Peixun, Jiang, Baoguo
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6993237/
https://ncbi.nlm.nih.gov/pubmed/32042324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.36272
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