Regulation of the ER Stress Response by the Ion Channel Activity of the Infectious Bronchitis Coronavirus Envelope Protein Modulates Virion Release, Apoptosis, Viral Fitness, and Pathogenesis

Coronavirus (CoV) envelope (E) protein is a small structural protein critical for virion morphogenesis and release. The recently characterized E protein ion channel activity (EIC) has also been implicated in modulating viral pathogenesis. In this study, we used infectious bronchitis coronavirus (IBV...

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Bibliographische Detailangaben
Veröffentlicht in:Front Microbiol
Hauptverfasser: Li, Shumin, Yuan, Lixia, Dai, Guo, Chen, Rui Ai, Liu, Ding Xiang, Fung, To Sing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6992538/
https://ncbi.nlm.nih.gov/pubmed/32038520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.03022
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