Tojapride prevents CaSR‐mediated NLRP3 inflammasome activation in oesophageal epithelium irritated by acidic bile salts

Impairment of the oesophageal epithelium in patients with reflux oesophagitis (RE) is a cytokine‐mediated injury rather than a chemical burn. The present study was conducted to explore CaSR/NLRP3 inflammasome pathway activation and cytokines IL‐1β and IL‐18 release in oesophageal epithelia injured b...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yin, Xiao‐Lan, Wu, Hao‐Meng, Zhang, Bei‐Huang, Zhu, Ning‐Wei, Chen, Ting, Ma, Xiang‐Xue, Zhang, Li‐Ying, Lv, Lin, Zhang, Min, Wang, Feng‐Yun, Tang, Xu‐Dong
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991659/
https://ncbi.nlm.nih.gov/pubmed/31859410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14631
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