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Physiological studies in heterozygous calcium sensing receptor (CaSR) gene-ablated mice confirm that the CaSR regulates calcitonin release in vivo

BACKGROUND: The calcium sensing receptor (CaSR) regulates serum calcium by suppressing secretion of parathyroid hormone; it also regulates renal tubular calcium excretion. Inactivating mutations of CaSR raise serum calcium and reduce urine calcium excretion. Thyroid C-cells (which make calcitonin) e...

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Bibliographic Details
Main Authors: Fudge, Neva J, Kovacs, Christopher S
Format: Artigo
Language:Inglês
Published: BioMed Central 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC419359/
https://ncbi.nlm.nih.gov/pubmed/15099400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-4-5
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