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The Extracellular Calcium-Sensing Receptor (CaSR) Is a Critical Modulator of Skeletal Development

The extracellular Ca(2+)-sensing receptor (CaSR) plays a nonredundant role in the functions of the parathyroid gland (PTG) and the kidney. Severe hyperparathyroidism, premature death, and incomplete gene excision in Casr(−/−) mice have precluded the assessment of CaSR function in other tissues. We g...

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Bibliografiske detaljer
Main Authors: Chang, Wenhan, Tu, Chialing, Chen, Tsui-Hua, Bikle, Daniel, Shoback, Dolores
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538864/
https://ncbi.nlm.nih.gov/pubmed/18765830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1159945
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