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Dual TBK1/IKKɛ inhibitor amlexanox attenuates the severity of hepatotoxin‐induced liver fibrosis and biliary fibrosis in mice

Although numerous studies have suggested that canonical IκB kinases (IKK) play a key role in the progression of liver fibrosis, the role of non‐canonical IKKε and TANK‐binding kinase 1 (TBK1) on the development and progression of liver fibrosis remains unclear. To demonstrate such issue, repeated in...

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Опубликовано в: :J Cell Mol Med
Главные авторы: Zhou, Zixiong, Qi, Jing, Zhao, Jing, Lim, Chae Woong, Kim, Jong‐Won, Kim, Bumseok
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991653/
https://ncbi.nlm.nih.gov/pubmed/31821710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14817
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