Comparison of Lemborexant With Placebo and Zolpidem Tartrate Extended Release for the Treatment of Older Adults With Insomnia Disorder: A Phase 3 Randomized Clinical Trial

IMPORTANCE: Insomnia disorder is prevalent and associated with health risks in older adults; however, efficacy and safety issues with existing treatments create significant unmet needs in this patient population. OBJECTIVE: To compare treatment with the orexin receptor antagonist lemborexant with pl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:JAMA Netw Open
Hauptverfasser: Rosenberg, Russell, Murphy, Patricia, Zammit, Gary, Mayleben, David, Kumar, Dinesh, Dhadda, Shobha, Filippov, Gleb, LoPresti, Antonia, Moline, Margaret
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Medical Association 2019
Schlagworte:
Original Investigation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6991236/
https://ncbi.nlm.nih.gov/pubmed/31880796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamanetworkopen.2019.18254
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