Lemborexant, A Dual Orexin Receptor Antagonist (DORA) for the Treatment of Insomnia Disorder: Results From a Bayesian, Adaptive, Randomized, Double-Blind, Placebo-Controlled Study

STUDY OBJECTIVES: To identify dose(s) of lemborexant that maximize insomnia treatment efficacy while minimizing next-morning residual sleepiness and evaluate lemborexant effects on polysomnography (PSG) measures (sleep efficiency [SE], latency to persistent sleep [LPS], and wake after sleep onset [W...

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Sleep Med
Hauptverfasser: Murphy, Patricia, Moline, Margaret, Mayleben, David, Rosenberg, Russell, Zammit, Gary, Pinner, Kate, Dhadda, Shobha, Hong, Quan, Giorgi, Luigi, Satlin, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Academy of Sleep Medicine 2017
Schlagworte:
Scientific Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656478/
https://ncbi.nlm.nih.gov/pubmed/29065953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5664/jcsm.6800
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