Objective Response Rate Among Patients With Locally Advanced or Metastatic Sarcoma Treated With Talimogene Laherparepvec in Combination With Pembrolizumab: A Phase 2 Clinical Trial

IMPORTANCE: Patients with advanced sarcoma have limited treatment options. Talimogene laherparepvec (T-VEC) has been shown to increase tumor-specific immune activation via augmenting antigen presentation and T-cell priming. OBJECTIVE: To examine whether T-VEC in combination with pembrolizumab is ass...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:JAMA Oncol
Main Authors: Kelly, Ciara M., Antonescu, Cristina R., Bowler, Timothy, Munhoz, Rodrigo, Chi, Ping, Dickson, Mark A., Gounder, Mrinal M., Keohan, Mary Louise, Movva, Sujana, Dholakia, Reena, Ahmad, Hamza, Biniakewitz, Matthew, Condy, Mercedes, Phelan, Haley, Callahan, Margaret, Wong, Phillip, Singer, Sam, Ariyan, Charlotte, Bartlett, Edmund K., Crago, Aimee, Yoon, Sam, Hwang, Sinchun, Erinjeri, Joseph P., Qin, Li-Xuan, Tap, William D., D’Angelo, Sandra P.
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2020
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990941/
https://ncbi.nlm.nih.gov/pubmed/31971541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2019.6152
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker