Silencing MicroRNA-137-3p, which Targets RUNX2 and CXCL12 Prevents Steroid-induced Osteonecrosis of the Femoral Head by Facilitating Osteogenesis and Angiogenesis

The main pathogenesis of steroid-induced osteonecrosis of the femoral head (SONFH) includes decreased osteogenic capacity of bone marrow-derived mesenchymal stem cells (BMSCs) and damaged blood supply to the femoral head. MicroRNAs (miRNAs) have been shown to play prominent roles in SONFH developmen...

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Dettagli Bibliografici
Pubblicato in:Int J Biol Sci
Autori principali: Kong, Lingchi, Zuo, Rongtai, Wang, Mengwei, Wang, Wenbo, Xu, Jia, Chai, Yimin, Guan, Junjie, Kang, Qinglin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990928/
https://ncbi.nlm.nih.gov/pubmed/32025213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.38713
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