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Exosomes derived from human CD34(+) stem cells transfected with miR-26a prevent glucocorticoid-induced osteonecrosis of the femoral head by promoting angiogenesis and osteogenesis
BACKGROUND: Damaged endothelial cells and downregulated osteogenic ability are two key pathogenic mechanisms of glucocorticoid (GC)-induced osteonecrosis of the femoral head (ONFH). Recent studies suggested that transplantation of CD34(+) stem cell-derived exosomes (CD34(+)-Exos) can treat ischemic...
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| Опубликовано в: : | Stem Cell Res Ther |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6858646/ https://ncbi.nlm.nih.gov/pubmed/31730486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1426-3 |
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