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Acid and inflammatory sensitisation of naked mole-rat colonic afferent nerves

Acid sensing in the gastrointestinal tract is required for gut homeostasis and the detection of tissue acidosis caused by ischaemia, inflammation and infection. In the colorectum, activation of colonic afferents by low pH contributes to visceral hypersensitivity and abdominal pain in human disease i...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Hockley, James RF, Barker, Katie H, Taylor, Toni S, Callejo, Gerard, Husson, Zoe M, Bulmer, David C, Smith, Ewan St. J
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990608/
https://ncbi.nlm.nih.gov/pubmed/31992138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806920903150
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