Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers

Acid-sensing ion channels (ASICs) form both homotrimeric and heterotrimeric ion channels that are activated by extracellular protons and are involved in a wide range of physiological and pathophysiological processes, including pain and anxiety. ASIC proteins can form both homotrimeric and heterotrim...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Schuhmacher, Laura-Nadine, Callejo, Gerard, Srivats, Shyam, Smith, Ewan St. John
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798305/
https://ncbi.nlm.nih.gov/pubmed/29237731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.807859
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