Depletion of MLKL inhibits invasion of radioresistant nasopharyngeal carcinoma cells by suppressing epithelial-mesenchymal transition

BACKGROUND: To examine whether MLKL participated in the invasion of radiosensitive nasopharyngeal carcinoma (NPC) cell (CNE-2) and radioresistant NPC cell (CR) through regulating epithelial-mesenchymal transition (EMT). METHODS: siRNA and CRISPR/Cas9 technique were used to decrease MLKL expression i...

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Xehetasun bibliografikoak
Argitaratua izan da:Ann Transl Med
Egile Nagusiak: Dong, Yuanli, Sun, Yun, Huang, Yangle, Fang, Xumeng, Sun, Pian, Dwarakanath, Bilikere, Kong, Lin, Lu, Jiade Jay
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: AME Publishing Company 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990020/
https://ncbi.nlm.nih.gov/pubmed/32042757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.11.104
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