Gentiopicroside (GENT) protects against sepsis induced by lipopolysaccharide (LPS) through the NF-κB signaling pathway

BACKGROUND: Sepsis is a high-mortality disease without effective therapeutic options. The hyperactivation of the monocyte-macrophage system, especially M1 macrophages, triggers the onset of septic shock. Gentiopicroside (GENT), the main active component in the traditional Chinese medicinal herb Radi...

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Dades bibliogràfiques
Publicat a:Ann Transl Med
Autors principals: Wang, Qiong, Zhou, Xin, Yang, Long, Luo, Maocai, Han, Lei, Lu, Yao, Shi, Qi, Wang, Yongjun, Liang, Qianqian
Format: Artigo
Idioma:Inglês
Publicat: AME Publishing Company 2019
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6990009/
https://ncbi.nlm.nih.gov/pubmed/32042747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.11.126
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