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A Hyaluronan-binding Peptide (P15-1) Reduces Inflammatory and Catabolic Events in IL-1β-treated Human Articular Chondrocytes

Inflammation plays a critical role in osteoarthritis (OA). It stimulates catabolic events in articular chondrocytes and prevents chondrogenic precursor cells from repairing cartilage lesions, leading to accelerated cartilage degradation. Therefore, the identification of novel factors that reduce cat...

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Vydáno v:Sci Rep
Hlavní autoři: Shortt, Claire, Luyt, Leonard G., Turley, Eva A., Cowman, Mary K., Kirsch, Thorsten
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989647/
https://ncbi.nlm.nih.gov/pubmed/31996703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-57586-7
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