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Annexin A6 regulates catabolic events in articular chondrocytes via the modulation of NF-κB and Wnt/ß-catenin signaling

Annexin A6 (AnxA6) is expressed in articular chondrocytes at levels higher than in other mesenchymal cell types. However, the role of AnxA6 in articular chondrocytes is not known. Here we show that complete lack of AnxA6 functions resulted in increased ß-catenin activation in Wnt3a-treated murine ar...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Minashima, Takeshi, Kirsch, Thorsten
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957413/
https://ncbi.nlm.nih.gov/pubmed/29771996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197690
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